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Table 2 Risk and crude and adjusted odds ratios for blood transfusion within 14 days of surgery among 22,238 breast cancer patients, according to use of selected prescription drugs

From: Use of prescription drugs and risk of postoperative red blood cell transfusion in breast cancer patients: a Danish population-based cohort study

 

Transfused patients, N

All patients, N

Risk (%)

Crude OR (95% CI)

Adjusted OR* (95% CI)

Estimate

Estimate

Aspirin

 Nonusers

232

20,902

1.1

1.0 (ref)

1.0

 Users

47

1336

3.5

3.2 (2.4–4.5)

1.9 (1.4–2.7)

NSAIDs

 Nonusers

247

20,464

1.2

1.0

1.0

 Users

32

1774

1.8

1.5 (1.0–2.2)

1.4 (0.9–2.0)

SSRIs

 Nonusers

260

21,158

1.2

1.0

1.0

 Users

19

1080

1.8

1.4 (0.9–2.3)

1.2 (0.7–1.9)

Statins

 Nonusers

248

20,209

1.2

1.0

1.0

 Users

31

2029

1.5

1.2 (0.9–1.8)

1.0 (0.7–1.4)

  1. NSAIDs nonsteroidal anti-inflammatory drugs, SSRIs selective serotonin reuptake inhibitors
  2. *Odds ratio (OR) adjusted for age, cancer stage, and Charlson Comorbidity Index score