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Table 2 Association of density (combined BI-RADS and Parenchymal Pattern) with fibrosis and involution combination

From: Association between mammographic breast density and histologic features of benign breast disease

 

Age-adjusted and BMI-adjusted

Fully adjusteda

Covariate

Total N = 3400

Events N = 2163

Odds ratio (95% CI)

p value

Odds ratio (95% CI)

p value

Involution/Fibrosis

   

<.001

 

<.001

Complete/No

468

183 (39.1%)

1.00 (ref)

 

1.00 (ref)

 

Complete/Yes

524

330 (63.0%)

2.46 (1.88, 3.20)

 

2.54 (1.94, 3.33)

Partial/No

509

262 (51.5%)

1.19 (0.91, 1.56)

 

1.13 (0.86, 1.49)

Partial/Yes

1411

1014 (71.9%)

2.73 (2.17, 3.44)

 

2.43 (1.88, 3.12)

None/No

256

183 (71.5%)

1.83 (1.27, 2.63)

 

1.85 (1.28, 2.68)

None/Yes

232

191 (82.3%)

3.52 (2.33, 5.30)

 

3.08 (2.02, 4.71)

  1. BI-RADS Breast Imaging Reporting and Data Systems, BMI body mass index
  2. aIncludes all covariates from Table 1 that remained statistically significant after age and BMI adjustment