Parameter

Standardized odds ratio

95% CI for odds ratio

χ^{2}

P value

mC

95% CI for mC


Risk score

1.36

(1.20–1.55)

22.39

2.22E06

0.58

(0.54– 0.62)

Coarseness

1.06

(0.92–1.22)

0.61

4.34E01

0.50

(0.46– 0.54)

Contrast

0.87

(0.76–0.99)

4.33

3.75E02

0.46

(0.42– 0.50)

SD

1.01

(0.89–1.15)

0.03

8.55E01

0.50

(0.45– 0.54)

Sum average 16

1.29

(1.14–1.47)

15.37

8.85E05

0.58

(0.54– 0.62)

Sum average 32

1.32

(1.1–1.50)

17.55

2.80E05

0.58

(0.53– 0.62)

Sum average 64

1.38

(1.21–1.57)

23.81

1.06E06

0.59

(0.55–0.63)

Volumetric PD

1.27

(1.11–1.46)

11.84

5.80E04

0.57

(0.53– 0.61)

 Total number of observations (N) = 1248, including 317 cases and 931 controls. Standardized odds ratio is the change in odds for a standard deviation (in controls) increase in predictors, adjusted for age and body mass index. Sum average 16, 32 and 64 are the texture feature sum average using images downsized by a factor of 16, 32 and 64.

PD percent density, CI confidence interval, mC matched concordance index, SD standard deviation