Table 4 Comparison of immune gene expression between high versus low 12-gene chemokine signature scores in breast cancer
Immune genes | Mean values CS high | Mean values CS low | Adjusted p value |
|---|---|---|---|
BTLA | 4.374103903 | 3.429457529 | 1.24E-30 |
BTLA | 5.104717271 | 3.593084013 | 1.87E-41 |
CD14 | 10.54798175 | 10.07803072 | 1.00E-05 |
PD-L1 | 3.631025974 | 3.235645445 | 1.30E-12 |
PD-L1_2 | 7.857288587 | 6.090272006 | 1.47E-46 |
PD-L1_3 | 4.201128981 | 3.576133806 | 1.91E-19 |
CD69 | 8.500662981 | 7.112610181 | 9.03E-20 |
CTLA4 | 8.639718923 | 6.131656168 | 3.88E-59 |
CXCL12 | 5.909474361 | 5.901681942 | 1 |
CXCL12_2 | 10.2584955 | 10.211514 | 1 |
CXCL12_3 | 10.37964834 | 10.27661866 | 1 |
FAP | 10.84403166 | 10.76480457 | 1 |
Granzyme B | 8.749378335 | 5.759872516 | 6.87E-58 |
Granzyme B_2 | 8.799689613 | 5.545019987 | 3.45E-58 |
TIM3 | 8.841433445 | 8.110355729 | 1.97E-15 |
IDO1 | 8.966759748 | 5.712505632 | 6.00E-60 |
Interferon gamma | 5.094852239 | 3.264361445 | 6.63E-38 |
IL10 | 3.717511361 | 3.298523542 | 6.72E-10 |
IL2 | 2.964185658 | 2.676063232 | 1.25E-10 |
IL4 | 2.703027632 | 2.795378406 | 0.215457875 |
IL6 | 6.746965877 | 5.733926619 | 7.80E-08 |
JAK1 | 5.3000556 | 5.132389587 | 0.094531305 |
JAK1_2 | 9.330956665 | 9.094484413 | 0.024599705 |
JAK1_3 | 8.237782039 | 7.989419813 | 0.019509776 |
JAK1_4 | 10.80787464 | 10.7258152 | 1 |
LAG3 | 6.455917471 | 4.991195632 | 1.00E-43 |
LEM | 3.0760666 | 3.059619619 | 1 |
LEM_2 | 6.110419432 | 6.080285335 | 1 |
LEM_3 | 9.176335942 | 9.183974716 | 1 |
LEM_4 | 9.772502419 | 9.798403587 | 1 |
MICA | 8.81120191 | 8.799736368 | 1 |
MICA_2 | 4.690884181 | 4.882048935 | 1 |
MICA_3 | 4.891286084 | 5.075915484 | 1 |
MICA_4 | 8.791930277 | 8.781289103 | 1 |
MICA_5 | 4.693718703 | 4.827482226 | 1 |
MICA_6 | 9.571045 | 9.576738355 | 1 |
MICA_7 | 9.358850632 | 8.743868929 | 4.28E-07 |
CD56 | 5.580049794 | 5.914039671 | 1 |
CD56_2 | 4.629692439 | 4.864664335 | 1 |
CD56_3 | 3.710274097 | 3.817752942 | 0.453890338 |
CD56_4 | 5.035893445 | 5.352795768 | 1 |
CD56_5 | 5.70368229 | 6.044969677 | 1 |
NFKB | 9.915169981 | 9.803810142 | 0.846175728 |
NOS1 | 2.902139606 | 2.921106129 | 1 |
NOS1_2 | 2.673781071 | 2.701705103 | 1 |
NOS1_3 | 2.993182194 | 2.955307058 | 1 |
PD-1 | 4.767050374 | 4.533298226 | 6.38E-07 |
CD31 | 8.753703548 | 8.316285368 | 4.15E-05 |
CD31_2 | 9.199703387 | 8.773391155 | 2.09E-06 |
CD31_3 | 11.64218184 | 11.36531043 | 0.001319025 |
CD31_4 | 9.182763284 | 8.7672612 | 1.42E-05 |
PRF1 | 9.356943658 | 7.50412171 | 3.40E-47 |
STAT1 | 11.75385782 | 10.98503868 | 1.18E-40 |
STAT1_2 | 10.51426123 | 8.908289794 | 6.77E-47 |
STAT1_3 | 4.153055619 | 4.103139297 | 1 |
STAT1_4 | 8.731805852 | 8.584214968 | 0.320434448 |
STAT1_5 | 10.17262105 | 10.11776818 | 1 |
LIGHT | 5.336076219 | 4.766262271 | 7.19E-20 |
VEGA | 8.954027852 | 8.900788865 | 1 |
VEGA_2 | 10.5322381 | 10.51156299 | 1 |
VEGA_3 | 9.817599665 | 9.782464335 | 1 |