EZH2 expression | By category | Per 5% increase | ||||
---|---|---|---|---|---|---|
≤10% | 11–20% | >20% | P value for trend | P value | ||
Epithelium | ||||||
Number of subjects (cases/controls) | 48/184 | 10/55 | 16/30 | 74/269 | ||
Model 1a | Ref. | 0.70 (0.32–1.54) | 2.44 (1.15–5.17) | 0.078 | 1.17 (1.03–1.34) | 0.021 |
Model 2b | Ref. | 0.73 (0.3–1.63) | 2.67 (1.24–5.76) | 0.053 | 1.20 (1.04– 1.38) | 0.010 |
Model 3c | Ref. | 0.79 (0.32–1.96) | 2.95 (1.1–7.84) | 0.092 | 1.22 (1.02–1.46) | 0.026 |
Stroma | ||||||
Number of subjects (cases/controls) | 53/208 | 20/72 | 5/12 | 78/292 | ||
Model 1a | Ref. | 1.06 (0.58–1.96) | 1.94 (0.62–6.07) | 0.379 | 1.12 (0.93–1.35) | 0.230 |
Model 2b | Ref. | 1.20 (0.6 –2.23) | 2.13 (0.67–6.80) | 0.227 | 1.15 (0.95–1.39) | 0.147 |
Model 3c | Ref. | 1.32 (0.61–2.85) | 2.45 (0.64–9.37) | 0.189 | 1.18 (0.94–1.49) | 0.157 |