Prognostic role of neutrophil-to-lymphocyte ratio in breast cancer: a systematic review and meta-analysis

Breast Cancer Research

Table 4 Detailed characteristics of included studies

Author	Year	Number of patients	Disease stage	NLR cutoff value	Median age (years)	Breast cancer subtype (%)			Grade (%)		Postmenopausal (%)	Median follow-up (years)
Author	Year	Number of patients	Disease stage	NLR cutoff value	Median age (years)	ER+	HER-2+	Triple negative	Grade 1–2	Grade 3	Postmenopausal (%)	Median follow-up (years)
Asano et al. [12]	2016	61	Early	3.0	n/a	0	0	100	72	28	36	3.1
Azab et al. [23]	2012	316	Mixed	3.3	n/a	83	17	n/a	70	30	n/a	3.8
Azab et al. [13]	2013	437	Mixed	3.3	64	76	n/a	n/a	n/a	n/a	n/a	5
Bozkurt et al. [24]	2015	85	Early	2.0	n/a	0	0	100	31	69	69	n/a
Dirican et al. [25]	2015	1527	Mixed	4.0	n/a	68	17	n/a	80	20	44	2.5
Forget et al. [10]	2014	720	Early	3.3	n/a	84	9	n/a	61	39	n/a	5.8
Hong et al. [29]	2015	487	Early	1.9	55	67	21	19	73	27	42	4.6
Jia et al. [14]	2015	1570	Early	2.0	47	n/a	22	14	62	38	n/a	6.6
Koh et al. [8]	2014	157	Early	2.3	44	n/a	0	0	80	20	n/a	1.8
Koh et al. [15]	2015	1435	Mixed	5.0	52	55	36	100	56	44	n/a	n/a
Nakano et al. [9]	2015	167	Early	2.5	58	78	18	n/a	80	20	25	7.2^a
Noh et al. [26]	2013	442	Early	2.5	50	71	29	18	71	29	n/a	5.9
Pistelli et al. [27]	2015	90	Early	3.0	53	0	0	100	10	90	40	4.5
Rimando et al. [28]	2016	461	Mixed	3.8	58	74	n/a	n/a	51	49	n/a	5.1
Yao et al. [11]	2014	608	Early	2.6	53	66	25	16	n/a	n/a	48	3.5

ISSN: 1465-542X