Table 4 Breast cancer incidence cross-classified by 10-year risk groups from the Tyrer-Cuzick and Gail models when combined with breast density
| Â | Risk model combined with density (10-year risk) | ||||||
|---|---|---|---|---|---|---|---|
Risk model | <1 % | 1–2 % | 2–3.5 % | 3.5–5 % | 5–8 % | >8 % | Total |
Tyrer-Cuzick | |||||||
<1 % | 0/60 (0.0 %) | 0/18 (0.0 %) | Â | Â | Â | Â | 0/78 (0.0 %) |
1–2 % | 4/700 (0.6 %) | 60/6910 (0.9 %) | 18/1976 (0.9 %) | 2/85 (2.4 %) | 0/8 (0.0 %) |  | 84/9679 (0.9 %) |
2–3.5 % | 0/6 (0.0 %) | 69/7425 (0.9 %) | 221/16,515 (1.3 %) | 75/3807 (2.0 %) | 16/652 (2.5 %) | 1/24 (4.2 %) | 382/28,429 (1.3 %) |
3.5–5 % |  | 0/29 (0.0 %) | 21/2689 (0.8 %) | 66/3139 (2.1 %) | 35/1508 (2.3 %) | 2/139 (1.4 %) | 124/7504 (1.7 %) |
5–8 % |  |  | 3/144 (2.1 %) | 20/1181 (1.7 %) | 48/2257 (2.1 %) | 16/758 (2.1 %) | 87/4340 (2.0 %) |
>8 % | Â | Â | Â | 0/2 (0.0 %) | 5/172 (2.9 %) | 15/424 (3.5 %) | 20/598 (3.3 %) |
Total | 4/766 (0.5 %) | 129/14,382 (0.9 %) | 263/21324 (1.2 %) | 163/8214 (2.0 %) | 104/4597 (2.3 %) | 34/1345 (2.5 %) | 697/50,628 (1.4 %) |
Gail | |||||||
<1 % | Â | Â | Â | Â | Â | Â | Â |
1–2 % | 0/17 (0.0 %) | 5/601 (0.8 %) | 5/257 (1.9 %) | 0/14 (0.0 %) |  |  | 10/889 (1.1 %) |
2–3.5 % | 0/1 (0.0 %) | 33/4286 (0.8 %) | 170/14,115 (1.2 %) | 62/3894 (1.6 %) | 15/756 (2.0 %) | 0/42 (0.0 %) | 280/23,094 (1.2 %) |
3.5–5 % |  | 1/90 (1.1 %) | 68/7048 (1.0 %) | 118/7751 (1.5 %) | 75/3533 (2.1 %) | 11/315 (3.5 %) | 273/18,737 (1.5 %) |
5–8 % |  |  | 3/277 (1.1 %) | 21/1851 (1.1 %) | 63/3610 (1.7 %) | 20/1105 (1.8 %) | 107/6843 (1.6 %) |
>8 % | Â | Â | Â | 0/15 (0.0 %) | 8/316 (2.5 %) | 19/734 (2.6 %) | 27/1065 (2.5 %) |
Total | 0/18 (0.0 %) | 39/4977 (0.8 %) | 246/21,697 (1.1 %) | 201/13,525 (1.5 %) | 161/8215 (2.0 %) | 50/2196 (2.3 %) | 697/50,628 (1.4 %) |