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Fig. 3 | Breast Cancer Research

Fig. 3

From: Transformation of enriched mammary cell populations with polyomavirus middle T antigen influences tumor subtype and metastatic potential

Fig. 3

Tumor microarray gene expression profiling. Tumors were analyzed by microarray gene expression profiling and hierarchically clustered with mouse mammary tumor models using an intrinsic gene set identified by Herschkowitz et al. [7]. Vertical lines indicate individual tumors. Each enriched mammary epithelial cell population is indicated by a different color: green = luminal CD133+; blue = luminal CD133−; red = basal; black = stem cells. Mouse mammary tumor models that generate molecularly luminal tumors are shown in dark blue, and those predominantly within the basal subgroup are displayed in dark red. Normal mouse mammary tissue is represented in brown (n = number of tumors). DMBA 7,12-dimethylbenz[a]anthracene, MMTV mouse mammary tumor virus, PyMT polyomavirus middle T antigen

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