Fig. 1

Differential microRNA expression by mammary cellular subsets. a Micro-dissection of terminal end buds (TEBs) and mature ducts from 5-week-old GFP+ mice before performing miRNA expression profiling. b Unsupervised hierarchical clustering of microRNAs reveals groups of microRNAs with tissue-specific expression. c Validation of candidate microRNA expression using stemloop quantitative RT-PCR. The t test was performed: *p <0.05 indicates significant difference comparing candidate miRNA expression in TEBs with mature ducts