Table 2 Mechanisms of E-cadherin loss
Reference | Mechanism | Sample size | Percentage E-cadherin loss |
|---|---|---|---|
Vos et al. 1997 [97] | LOH | 7 | 86Â % |
Palacios et al. 2003 [98] | LOH | 7 | 100Â % |
Sarrió et al. 2003 [99] | LOH | 9 | 100 % |
Mastracci et al. 2005 [100] | LOH | 13 | 15Â % |
Vos et al. 1997 [97] | Mutation | 2 | 100Â % |
Rieger-Christ et al. 2001 [101] | Mutation | 21 | 38Â % |
Sarrió et al. 2003 [99] | Mutation | 3 | 100 % |
Mastracci et al. 2005 [100] | Mutation | 14 | 100Â % |
Sarrió et al. 2003 [99] | Methylation | 9 | 11 % |
Morrogh et al. 2012 [77] | Transcription | 36 | 100Â % |