Figure 3From: Modulation of tumor fatty acids, through overexpression or loss of thyroid hormone responsive protein spot 14 is associated with altered growth and metastasisTumor latency, multiplicity, and proliferation in Neu and Neu/S14 mice. (A) Kaplan-Meier survival curve of tumor latency in Neu and Neu/S14 mice. Median times to tumor onset were 238 days (Neu/S14) and 279 days (Neu); hazard ratio (HR) 0.2645 (0.1087 to 0.6435); log rank P-value = 0.0034. (B) Number of tumors per mouse at sacrifice. P = 0.52. (C) Quantification of Ki67 immunohistochemistry (number of positive nuclei out of total) in tumors; n = 5 mice per group; graph is mean + standard error of the mean; P = 0.02.Back to article page