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Figure 3 | Breast Cancer Research

Figure 3

From: Modulation of tumor fatty acids, through overexpression or loss of thyroid hormone responsive protein spot 14 is associated with altered growth and metastasis

Figure 3

Tumor latency, multiplicity, and proliferation in Neu and Neu/S14 mice. (A) Kaplan-Meier survival curve of tumor latency in Neu and Neu/S14 mice. Median times to tumor onset were 238 days (Neu/S14) and 279 days (Neu); hazard ratio (HR) 0.2645 (0.1087 to 0.6435); log rank P-value = 0.0034. (B) Number of tumors per mouse at sacrifice. P = 0.52. (C) Quantification of Ki67 immunohistochemistry (number of positive nuclei out of total) in tumors; n = 5 mice per group; graph is mean + standard error of the mean; P = 0.02.

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