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Table 3 Correlation between miRNA levels and surface markers

From: MiR-183/-96/-182 cluster is up-regulated in most breast cancers and increases cell proliferation and migration

 

miR-96 (per million)

miR-182 (per million)

miR-183 (per million)

ER− (n = 185)

46.9 ± 37.1

42764.4 ± 29615.6

23463.0 ± 18606.7

ER + (n = 643)

40.5 ± 32.2*

49378.5 ± 32671.3*

17756.8 ± 12451.0***

PR+ (n = 265)

45.6 ± 34.7

45513.2 ± 32873.7

22037.2 ± 16212.9

PR + (n = 561)

40.2 ± 32.8*

49013.4 ± 31716.4

17628.8 ± 12993.5***

HER2− (n = 512)

40.7 ± 34.5

47943.7 ± 32825.1

18532.7 ± 14331.1

HER2+ (n = 144)

41.8 ± 32.5

44664.8 ± 28806.9

19404.0 ± 14591.3

  1. The expression of each miRNA in the miR-183/-96/182 cluster in different breast cancer subtypes based on their surface markers: Patient number is indicated in the first column. Data are presented as mean ± SD. Statistical probability (P) was expressed as *P<0.05, ***P<0.001. ER, estrogen receptor; PR, progesterone receptor; HER, human epidermal growth factor receptor.