SULT1A1*1/*1 genotype | SULT1A1*2 allele carriera | |||||
---|---|---|---|---|---|---|
Variable | Cases (n = 198) | Controls (n = 374) | ORb (95% CI) | Cases (n = 221) | Controls (n = 510) | ORb (95% CI) |
Never active | 86 | 159 | 1 (ref) | 88 | 209 | 1 (ref) |
Ever active | 112 | 215 | 0.92 (0.63–1.34) | 133 | 301 | 1.01 (0.73–1.42) |
Never active/passivec, d | 20 | 56 | 1 (ref) | 19 | 57 | 1 (ref) |
Former active | 44 | 94 | 1.23 (0.64–2.36) | 59 | 157 | 1.11 (0.60–2.06) |
Current active | 68 | 121 | 1.44 (0.76–2.71) | 74 | 144 | 1.51 (0.82–2.78) |
Average cigarettes per dayc, e | ||||||
>0–9 | 42 | 106 | 1.06 (0.55–2.03) | 52 | 154 | 0.99 (0.54–1.84) |
10–19 | 56 | 73 | 2.12 (1.10–4.07) | 60 | 99 | 1.75 (0.94–3.25) |
20+ | 14 | 34 | 1.05 (0.45–2.46) | 20 | 48 | 1.09 (0.51–2.32) |
Duration of smokingc, d | ||||||
1–15 years | 36 | 80 | 1.19 (0.61–2.34) | 46 | 145 | 0.97 (0.52–1.82) |
16+ years | 76 | 135 | 1.44 (0.77–2.69) | 87 | 156 | 1.62 (0.89–2.95) |
Age at first cigarettec, d | ||||||
9–15 years | 21 | 47 | 1.09 (0.51–2.35) | 20 | 63 | 0.84 (0.40–1.79) |
16–18 years | 56 | 109 | 1.33 (0.70–2.52) | 70 | 145 | 1.42 (0.77–2.62) |
19+ years | 35 | 59 | 1.51 (0.75–3.05) | 43 | 93 | 1.42 (0.74–2.72) |
Pack-yearsc, e | ||||||
>0–10 | 59 | 129 | 1.22 (0.65–2.27) | 76 | 191 | 1.15 (0.64–2.07) |
11+ | 53 | 84 | 1.77 (0.91–3.42) | 56 | 110 | 1.43 (0.77–2.67) |
Passive smokingf | ||||||
No | 20 | 57 | 1 (ref) | 19 | 57 | 1 (ref) |
Yes | 66 | 102 | 1.69 (0.89–3.21) | 69 | 152 | 1.40 (0.74–2.64) |
Duration of passive exposure in adulthoodf, g, h | ||||||
1–13 years | 29 | 40 | 1.91 (0.91–4.00) | 33 | 70 | 1.47 (0.72–2.98) |
14+ years | 32 | 47 | 1.66 (0.79–3.48) | 29 | 61 | 1.47 (0.70–3.10) |
Cumulative lifetime exposure (in hours/day-years)f, g, i | ||||||
1–55 | 22 | 49 | 1.13 (0.52–2.38) | 37 | 76 | 1.76 (0.89–3.50) |
56+ | 43 | 52 | 2.12 (1.06–4.25) | 32 | 71 | 1.39 (0.68–2.83) |