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Table 2 Relation of Q356R and breast cancer risk in the Nurses' Health Study

From: Haplotype analysis of common variants in the BRCA1 gene and risk of sporadic breast cancer

Genotype Case (frequency)a Control (frequency)a OR (95% CI) ORb (95% CI)
Q356Q 1065 (86.23) 1413 (87.01) 1.00 (reference) 1.00 (reference)
Q356R 165 (13.36) 206 (12.68) 1.06 (0.85–1.32) 1.05 (0.84–1.32)
R356R 5 (0.4) 5 (0.31) 1.33 (0.38–4.59) 1.67 (0.44–6.35)
  1. CI, confidence interval; OR, odds ratio.
  2. aSamples lacking genotype information were removed from analysis.
  3. bLogistic regression controlling for age, age of menopause, post-menopausal hormone use, age at first birth, parity, family history of breast cancer, and history of benign breast disease.