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Table 3 Interferon-γ ELISPOT assay after vaccination with virus-like replicon particles (VRP)-neu or VRP-hemagglutinin (HA)

From: Alphavirus replicon particles containing the gene for HER2/neuinhibit breast cancer growth and tumorigenesis

Effector:stimulator

VRP-neu (spots/106 cells)

VRP-HA (spots/106 cells)

100:1

99a

11

50:1

126a

17

25:1

129a

25

Effector only

2

5

Concanavalin A

256a,b

Not determined

  1. a P = 0.05 by Student's t test.
  2. bSpleen cells stimulated with concanavalin A as a positive control for the assay.