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Table 1 Tetramer analysis of CD8+ T cells after vaccination three times with virus-like replicon particles (VRP)-neu or VRP-hemagglutinin (HA)

From: Alphavirus replicon particles containing the gene for HER2/neuinhibit breast cancer growth and tumorigenesis

Vaccination

CD8+ cells (%)

Tetramer-positive CD8+ cells (%)

Tetramer-positive CD8+/CD8+ (%)

neu-specific tetramer

   

   VRP-neu

15.98

0.38

2.38

   VRP-HA

23.06

0.05

0.22

HA-specific tetramer

   

   VRP-neu

16.01

0.06

0.37

   VRP-HA

17.46

0.50

2.79