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Table 3 Comparison of models

From: Ratios of involved nodes in early breast cancer

Patients studied

R2 N

Hazard ratios (95% confidence interval)

 
  

np

nx

np/nx (%)

L

All cases

   1: no nodal variables

0.069

    

   2: np

0.093

1.093 (1.090–1.097)

   

   3: nx

0.069

 

0.998 (0.995–1.001)

  

   4: np, nx

0.096

1.112 (1.108–1.116)

0.970 (0.966–0.974)

  

   5: np/nx (%)

0.104

  

1.023 (1.022–1.024)

 

   6: L

0.108

   

1.459 (1.442–1.477)

   7: np, np/nx (%)

0.104

1.010 (1.004–1.017)

 

1.021 (1.020–1.023)

 

   8: nx, np/nx (%)

0.104

 

1.002 (0.999–1.005)

1.023 (1.022–1.024)

 

   9: np, L

0.108

0.998 (0.992–1.005)

  

1.466 (1.435–1.497)

   10: nx, L

0.109

 

1.009 (1.006–1.013)

 

1.462 (1.445–1.479)

   11: np, nx, np/nx (%)

0.104

1.013 (1.004–1.022)

0.998 (0.994–1.002)

1.021 (1.019–1.022)

 

   12: np, nx, L

0.109

0.967 (0.957–0.976)

1.021 (1.017–1.026)

.

1.599 (1.554–1.646)

Node-positive patients

   1: no nodal variables

0.067

    

   2: np

0.095

1.066 (1.062–1.071)

   

   3: nx

0.067

 

0.996 (0.992–1.000)

  

   4: np, nx

0.102

1.088 (1.083–1.093)

0.966 (0.961–0.971)

  

   5: np/nx (%)

0.108

  

1.017 (1.016–1.018)

 

   6: L

0.108

   

1.379 (1.355–1.403)

   7: np, np/nx (%)

0.109

1.013 (1.006–1.020)

 

1.015 (1.014–1.017)

 

   8: nx, np/nx (%)

0.108

 

1.005 (1.001–1.009)

1.017 (1.016–1.018)

 

   9: np, L

0.108

1.008 (1.001–1.016)

  

1.344 (1.306–1.384)

   10: nx, L

0.108

 

1.005 (1.001–1.009)

 

1.381 (1.357–1.405)

   11: np, nx, np/nx (%)

0.109

1.016 (1.005–1.028)

0.998 (0.991–1.004)

1.015 (1.013–1.017)

 

   12: np, nx, L

0.108

1.003 (0.990–1.017)

1.003 (0.996–1.010)

 

1.366 (1.304–1.431)

Node-negative patients

   1: no nodal variables

0.045

NA

   

   3: nx

0.045

NA

0.991 (0.986–0.997)

  

   6: L

0.045

NA

  

1.150 (1.058–1.249)

   10: nx, L

0.045

NA

1.001 (0.984–1.019)

 

1.169 (0.902–1.514)

  1. Shown are all nodal status combined, and node-positive patients and node-negative patients separately. A hazard ratio >1 indicates increased risk for death from breast cancer. All models are multivariate, adjusting for the effect of covariates listed in the Methods section: tumor size, age at diagnosis, year of diagnosis, registry area, race, marital status, tumor topography, histologic type and grade, estrogen and progesterone receptor status, type of primary surgery, and administration of postoperative radiotherapy. NA, not applicable; np, number of involved nodes; nx, number of nodes examined; np/nx (%), percentage of nodes involved; L, log-odds of node involvement; R2 N, Nagelkerke R2 index of global model fit (0 = lack of fit, 1 = perfect fit).