From: Frequency of the ATM IVS10-6T→G variant in Australian multiple-case breast cancer families
Characteristic | GHSV, RMH and WHa | SAFCS | Total |
---|---|---|---|
Total number of families | 294 | 201 | 495 |
Average number of female breast cancer cases per family | 3.4 | 3.2 | |
Average number of ovarian cancer cases per family | 0.42 | 0.25 | |
Average age of index case breast cancer diagnosis (years) | 45.1 | 48.2 | |
High risk | 270 (91.8%) | 179 (89.0%) | 449 (90.7%) |
With breast and ovarian cancer cases | 77 (26.2%) | ||
With breast cancer cases and high-risk featuresb | 142 (48.3%) | ||
With breast cancer cases and no high-risk featuresc | 51 (17.3%) | ||
Moderate risk | 22 (7.5%) | 15 (7.5%) | 37 (7.5%) |
Risk status not known | 2 (0.7%) | 7 (3.5%) | 9 (1.8%) |