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Table 2 Association of DAX-1 with various clinicopathological factors and with estrogen receptor-α, estrogen receptor-β and androgen receptor status

From: DAX-1 expression in human breast cancer: comparison with estrogen receptors ER-α, ER-β and androgen receptor status

Parameter

n

Negative

Nuclear location

P

Cytoplasmic location

P

Age (years)

      

   ≤50

11

5

4

 

2

 

   >50

28

9

11

0.699

8

0.652

TNM class

      

   T1

19

10

7

 

2

 

   T2

16

6

6

 

4

 

   T3

2

1

1

 

0

 

   T4

2

0

0

0.8486

2

0.216

Nodal status (%)

      

   ≤33

26

14

6

 

6

 

   33–90

10

2

7

 

1

 

   >90

3

0

1

<0.05

2

0.1439

Histological type

      

   Ductal

24

10

9

 

5

 

   Lobular

15

4

6

0.699

5

0.4028

Disease-free duration (months)

      

   5–20

3

0

1

 

2

 

   20–30

10

2

5

 

3

 

   >30

26

11

9

0.3081

6

0.1713

ER-α

      

   -

10

5

3

 

2

 

   C

9

2

2

 

5

 

   N

20

7

10

0.6077

3

0.1649

ER-β

      

   -

23

9

7

 

7

 

   C

13

5

6

 

3

 

   N

3

1

2

0.7138

0

0.6766

AR

      

   -

20

12

6

 

2

 

   C

17

2

7

 

8

 

   N

2

0

2

<0.05

0

<0.001

  1. AR, androgen receptor; ER, estrogen receptor. C, cytoplasmic immunoreaction; N, nuclear immunostaining.