Skip to main content

Table 5 Proportions of BRCA1 and BRCA2 mutations in 19 male breast cancer probands classified by number of cancer patients in the family and age at disease diagnosis

From: BRCA1 and BRCA2 mutations in central and southern Italian patients

 

Age of proband at disease diagnosis

 

41-50 years

51 years or more

All ages

Cancer patients

BRCA1

BRCA2

BRCA1

BRCA2

BRCA1

BRCA2

in family*

[% (n)]

[% (n)]

[% (n)]

[% (n)]

[% (n)]

[% (n)]

One

0 (0/1)

0 (0/1)

0 (0/13)

8 (1/13)

0 (0/14)

7 (1/14)

Two or three

0 (0/3)

0 (0/3)

0 (0/2)

50 (1/2)

0 (0/5)

20 (1/5)

Total

0 (0/4)

0 (0/4)

0 (0/15)

13 (2/15)

0 (0/19)

10 (2/19)

  1. *Including proband; numbers of BRCA1- andBRCA2-positive cases over number of cases in each age subset are givenin brackets.