Morphological types of breast cancer in family members and multiple primary tumours: is morphology genetically determined?

Table 6 Kappa measures of agreement

		Kappa
Condition	n	All types	Ductal and lobular	Ductal, lobular and tubuloductal
1st/2nd invasive
Include all	907	0.22	0.23	0.18
Contralateral breast	653	0.38	0.56	0.47
<1 year interval	643	0.23	0.19	0.16
= 1 year interval	264	0.17	0.30	0.24
Contralateral breast and <1 year interval	416	0.47	0.63	0.54
Contralateral breast and = 1 year interval	237	0.20	0.40	0.32
In situ/invasive
Include all	465	0.01	0.18	0.08
Contralateral breast	153	0.21	0.21	0.17
<1 year interval	359	0.06	0.28	0.14
= 1 year interval	106	0.15	0.25	0.22
Contralateral breast and <1 year interval	93	0.33	0.27	0.21
Contralateral breast and = 1 year interval	60	0.02	0.13	0.12

ISSN: 1465-542X