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Table 3 Proteins altered with PRDX1 protein expression in cohort 3 after stratification into the ER-positive cohort

From: Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer

Protein*

Gene

FC#

Log2FC

Pvalue

Adjusted P value

ER-positive

     

PRDX1

PRDX1

1.7818

0.8334

<0.0001

<0.0001

Claudin-7

CLDN7

1.5971

0.6754

<0.0001

0.0003

ER-alpha

ESR1

1.5398

0.6227

0.0040

0.0169

MAPK-pT202-Y204

MAPK1 MAPK3

0.6505

-0.6204

0.0011

0.0075

Collagen-VI

COL6A1

0.6074

-0.7192

0.0015

0.0091

HSP70

HSPA1A

0.6057

-0.7233

0.0000

0.0007

  1. *Significant adjusted P value (P <0.05) highlighted in italics. #FC, fold change. ER, estrogen receptor; PRDX1, peroxiredoxin 1.