Skip to main content

Table 2 Adverse events during the PPV

From: Feasibility study of personalized peptide vaccination for metastatic recurrent triple-negative breast cancer patients

Adverse event

Grade 1

Grade 2

Grade 3

Grade 4

Injection site reaction

42

37

  

Constitutional symptom

    

  Fever

8

1

  

  Malaise

7

3

  

  Edema limbs

2

3

  

  Pain

5

   

  Tumor pain

4

9

  

Gastrointestinal

    

  Nausea

4

   

  Mucositis oral

 

1

  

  Abdominal pain

  

1

 

  Constipation

1

1

  

  Diarrhea

2

   

Respiratory

    

  Dyspnea

5

1

1

 

  Cough

5

   

  Hoarseness

2

   

  Pneumonitis

 

1

  

  Pleural effusion

1

   

  Hypoxia

 

1

2

 

Neurological

    

  Headache

1

1

  

  Dysgeusia

1

   

  Dizziness

2

1

  

  Peripheral sensory neuropathy

8

2

  

  Peripheral motor neuropathy

1

   

Endocrine disorder

    

  Hypothyroidism

 

1

  

Skin and subcutaneous

    

  Pruritis

33

3

  

  Urticaria

4

1

  

  Reproductive system

    

  Vaginal hemorrhage

2

   

  Vascular disorders

    

  Hot flashes

1

   

  Lymphedema

 

1

  

  Hypertension

 

1

  

Blood/Bone marrow

    

  Anemia

18

9

2

2

  Hemoglobin increased

1

   

  Leukocytopenia

22

11

4

 

  Neutropenia

2

6

5

1

  Lymphocytopenia

29

7

12

 

  Thrombocytopenia

6

 

1

 

Metabolism and nutrition

    

  Anorexia

2

   

  Hyponatremia

1

   

  Hyperkalemia

3

   

  Hypocalcemia

2

   

  Hyperglycemia

2

   

Laboratory

    

  AST increased

14

9

2

 

  ALT increased

19

4

2

 

  γ-GTP increased

7

3

2

 

  ALP increased

6

1

1

 

  Hyperbilirubinemia

3

1

1

 

  Creatinine increased

10

3

1

 

  Cholesterol high

4

   

  Hypoalbuminemia

46

7

  

  INR increased

1

1

1

 

  APTT increased

1

   
  1. ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; APTT, activated partial thromboplastin time; γ-GTP, gamma-glutamyl transpeptidase; INR, international normalized ratio; PPV, personalized peptide vaccination.
Back to article page

Breast Cancer Research

ISSN: 1465-542X

Contact us