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Figure 5 | Breast Cancer Research

Figure 5

From: Transforming growth factor beta receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer

Figure 5

TβRIII-KD modulates expression of ITGA2 in MSL cells. A-C) qRT-PCR analysis for ITGA2 mRNA expression from MSL TNBC cell lines with TβRIII-KD; graph bars represent the mean of three replicates with SEM error bars (**P = 0.003, ***P ≤0.0007 for a two-tailed Student’s t-test). D-F) Flow cytometry analysis for integrin-α2 in controls and TβRIII-KD MSL; arrow pointing to the right shows a shift towards an increase in protein levels of integrin-α2 in TβRIII-KD MSL cell lines. MSL, mesenchymal stem-like; SEM, standard error of the mean; TβRIII-KD, type III transforming growth factor-beta receptor knockdown.

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