Table 1 IPA upstream factor analysis of genes specifically expressed in PHBECs grown in co-cultures with hAMSCs

BNIP3L

Activated

3.05

5.60E-12

TP53

Activated

2.82

8.44E-12

let-7

Activated

2.01

1.12E-10

KDM5B

Activated

2.90

7.65E-07

CDKN2A

Activated

2.70

1.91E-06

MAPK14

Activated

2.28

5.65E-06

TCF3

Activated

3.32

1.49E-05

CEBPD

Activated

2.20

1.25E-04

PTHLH

Activated

2.20

1.47E-04

UXT

Activated

2.22

1.53E-04

TAZ

Activated

2.00

6.60E-04

MAP3K7

Activated

2.30

7.45E-04

SMARCB1

Activated

2.14

1.47E-03

P38 MAPK

Activated

2.29

6.01E-03

JUN

Activated

2.03

1.85E-02

Vegf

Inhibited

−2.35

1.70E-09

CCND1

Inhibited

−2.24

1.12E-08

MYC

Inhibited

−4.12

1.20E-08

E2F1

Inhibited

−2.89

2.51E-07

TBX2

Inhibited

−2.53

8.13E-07

FOXO1

Inhibited

−3.56

1.67E-05

MYBL2

Inhibited

−2.00

3.49E-03

MYCN

Inhibited

−2.38

7.17E-03

BMP7

Inhibited

−2.39

1.19E-02

CDKN1A

1.60

4.35E-21

HGF

−1.77

1.39E-10

CDK4

1.82E-09

TGFβ1

0.68

9.63E-08

RB1

1.14

8.23E-07

Tgf β

0.88

9.33E-06