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Figure 8 | Breast Cancer Research

Figure 8

From: JMJD2A contributes to breast cancer progression through transcriptional repression of the tumor suppressor ARHI

Figure 8

ARHI reverses JMJD2A-induced tumor progression in vivo in a xenograft model. MDA-MB-231 cells stably expressing JMJD2A alone or along with ARHI were constructed. Cells treated with empty vetor were used as control. (A) Periodic detection of tumor volume in three groups. (B) Tumors were dissected and each tumor in three groups was exhibited. (C) Tumors excised were weighed on day 27. (D) Breast cancer metastasis was observed and liver nodules were counted in three groups. Total nodule numbers were statistically analyzed. *P <0.05, **P <0.01. ARHI, Aplasia Ras homolog member I.

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Breast Cancer Research

ISSN: 1465-542X

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