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Figure 6 | Breast Cancer Research

Figure 6

From: GPR30 as an initiator of tamoxifen resistance in hormone-dependent breast cancer

Figure 6

Generation of cAMP mediated by GPR30 in MCF-7 and TAM-R cells. Cells were incubated for five minutes with 1 nM E2, 10 nM G1 or 1 μM Tam; ELISA was then performed after preparation of cell lysates. Each experiment was repeated at least three times. Data show means ± SD. *P <0.05 versus similarly treated MCF-7 cells. E2, 17β-estradiol; GPR30, G-protein coupled receptor 30; Tam, 4-hydroxytamoxifen; TAM-R, tamoxifen resistant.

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