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  • Poster presentation
  • Open Access

PB.32: Does vacuum-assisted biopsy decrease the B3 rate in stereotactic biopsy of breast lesions?

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Breast Cancer Research201315 (Suppl 1) :P32

  • Published:


  • Invasive Cancer
  • Preoperative Diagnosis
  • Breast Lesion
  • Core Needle Biopsy
  • Stereotactic Biopsy


Vacuum-assisted biopsy (VAB) systems have been shown to outperform 14G core needle biopsy (CNB) reducing the need for diagnostic or multiple surgeries. We introduced VAB in 2011 with the aim of reducing our B3 rate and increasing rate of preoperative diagnosis of invasive cancer.


Mammographic abnormalities requiring stereotactic biopsy in a defined period which had either 14G CNB or VAB were included. Data collated included mammographic findings, biopsy and surgical outcome.


Ninety 14G-CNBs (November 2010 to May 2011) were compared with 78 VABS (July 2012 to January 2013). There was no reduction in our B3 rate (12 and 13 cases respectively) although VAB had higher sensitivity with better correlation between biopsy diagnosis and surgical histology (77% compared with 42%). Four of 12 (25%) B3 lesions diagnosed following 14G CNB were upgraded to DCIS following surgical excision compared with no cases following VAB. Preoperative invasive malignancy diagnostic rates were unchanged, 15% of cases were upgraded in both groups.


VAB has not reduced our B3 rate but has increased the accuracy of our preoperative diagnosis of non-invasive cancer supporting current theories that patients who have undergone vacuum-assisted biopsy may not require surgical diagnostic excision. However, we recognise the number of cases is low and further cases will be analysed and presented.

Authors’ Affiliations

Charing Cross Hospital, West London Breast Screening Service, London, UK


© Seaton et al.; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.