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  • Poster presentation
  • Open Access

PB.06: Preliminary results in the performance comparison between the size ratio and colour scoring breast ultrasound elastographic techniques

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Breast Cancer Research201315 (Suppl 1) :P6

  • Published:


  • Gold Standard
  • Female Patient
  • Performance Comparison
  • Diagnostic Performance
  • Histological Diagnosis


There are a few breast ultrasound elastographic techniques that can help with distinguishing malignant breast lesions from benign ones. Two of the better known ones are the size ratio and colour scoring methods. The aim of this study is to prospectively compare the diagnostic performance of these two elastographic techniques.


Female patients referred to the radiology department for image-guided breast biopsy were prospectively evaluated with ultrasound elastography prior to biopsy following informed consent. The two elastographic methods were assessed on each breast lesion separately by different radiologists. A size ratio of ≥1.1 was taken to be malignant and <1.1 was benign. Colour scores of 1 to 3 were taken as benign and colour scores of 4 to 5 were considered malignant. Histological diagnosis was used as the gold standard. The sensitivity and specificity of both techniques were compared using the Fisher's exact test.


Sixty-five breast lesions in 63 women were evaluated at the interim stage of the study. There were 21 malignant and 44 benign breast lesions. The sensitivity and specificity of the size ratio technique were 100% (21/21) and 81.8% (36/44). The sensitivity and specificity of the colour scoring method were 57.1% (12/21, P = 0.001) and 86.4% (38/44, P = 0.772).


The preliminary results indicate that the size ratio elastographic technique is more sensitive and accurate than the colour scoring method. A larger study is ongoing.

Authors’ Affiliations

Singapore General Hospital, Singapore


© Leong et al.; licensee BioMed Central Ltd. 2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.