MAPP Name | number changed | number measured | % changed | Z-scorea |
---|---|---|---|---|
Up-regulated | ||||
Complement and coagulation cascades | 15 | 50 | 30.00% | 5.65 |
Senescence and autophagy | 18 | 100 | 18.00% | 3.61 |
RANKL/RANK signalling pathway | 11 | 50 | 22.00% | 3.58 |
Complement activation, classical pathway | 5 | 15 | 33.33% | 3.55 |
Matrix metalloproteinases | 7 | 29 | 24.14% | 3.14 |
TGF beta signalling pathway | 18 | 113 | 15.93% | 3.03 |
Inflammatory response pathway | 7 | 30 | 23.33% | 3.03 |
Oxidative stress | 6 | 24 | 25.00% | 3.01 |
Adipogenesis | 19 | 125 | 15.20% | 2.89 |
Endochondral ossification | 11 | 61 | 18.03% | 2.82 |
TWEAK signalling pathway | 8 | 40 | 20.00% | 2.73 |
SREBP signalling | 6 | 28 | 21.43% | 2.56 |
Down-regulated | Â | Â | Â | Â |
Cell cycle | 17 | 95 | 17.89% | 6.62 |
DNA replication | 9 | 41 | 21.95% | 5.61 |
Nucleotide metabolism | 5 | 17 | 29.41% | 5.12 |
Proteasome degradation | 10 | 57 | 17.54% | 4.97 |
Electron transport chain | 10 | 81 | 12.35% | 3.61 |
G1 to S cell cycle control | 7 | 67 | 10.45% | 2.51 |