Table 4 Associations of categorical and continuous percent density analysis from processed (proc) full-field digital mammography (FFDM) representation with breast cancer (n = 180 case and matched control pairs).

1

30

1.00 (Ref.)

1.00 (Ref.)

1.00 (Ref.)

1.00 (Ref.)

2

52

1.70 (0.93, 3.13)

2.16 (1.13, 4.12)

2.24 (1.16, 4.30)

2.59 (1.32, 5.09)

3

44

1.51 (0.81, 2.81)

2.22 (1.11, 4.44)

2.35 (1.16, 4.77)

2.70 (1.30, 5.62)

4

54

1.90 (0.98, 3.67)

3.14 (1.49, 6.60)

3.42 (1.59, 7.39)

3.99 (1.80, 8.84)

BMI^a

n/a

1.50 (1.18, 1.90)

1.41 (1.08, 1.84)

1.39 (1.06, 1.81)

BA^a

n/a

n/a

1.14 (0.86, 1.51)

1.18 (0.89, 1.57)

Menopause^b

n/a

n/a

n/a

2.82 (1.16, 6.84)

AUC^c

0.556

0.636

0.638

0.647

Continuous PD_proc

Unadjusted OR (95% CI)

BMI adjusted OR (95% CI)

BMI, BA adjusted OR (95% CI)

BMI, BA, menopause adjusted OR (95% CI)

PD^a

1.32 (1.02, 1.69)

1.63 (1.22, 2.18)

1.67 (1.24, 2.25)

1.68 (1.24, 2.28)

BMI^a

n/a

1.53 (1.20, 1.94)

1.45 (1.10, 1.89)

1.42 (1.08, 1.86)

BA^a

n/a

n/a

1.13 (0.85, 1.48)

1.14 (0.86, 1.51)

Menopause^b

n/a

n/a

n/a

2.19 (0.93, 5.19)

AUC^c

0.550

0.628

0.635

0.643