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Table 3 Parameter definitions for base-case and sensitivity analyses of overdiagnosismodel.

From: Modelling the overdiagnosis of breast cancer due to mammography screening in womenaged 40 to 49 in the United Kingdom

  Screening test Mean sojourn time (years)
  sensitivity (%) 40 to 49 50-59
Invasive Invasive In-situ NPIS PIS PIBC NPIS PIS PIBC
Base case Median1 Median 3 0.175 1.825
Long MST Median Upper limit2 5 0.25 2.75
Short MST Median Lower limit3 2 0.1 1.5
High sensitivity 100 100 Median 3 0.175 1.825
Low sensitivity Lower limit Median 3 0.175 1.825
Low sensitivity, long MST Lower limit Upper limit 5 0.25 2.75
High sensitivity, long MST 100 100 Upper limit 5 0.25 2.75
  1. 1,2,3Refers to the median, upper limit, and lower limit of resultsfrom parameter estimation model, respectively. MST, median sojourn time; NPIC,non-progressive in situ; PIBC, preclinical invasive breast cancer; PIS,preclinical progressive in situ.