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Table 1 Distribution of risk factors in 1857 subjects from MNYR/New York site of the BCFR.

From: Breast cancer risk assessment across the risk continuum: genetic and nongenetic risk factors contributing to differential model performance

 

Unaffected after 10 yrs

Follow-up <10 yrs

Died within 10 yrs

Breast cancer within 10 yrs

Total

All subjects

730

989

55

83

1857

Age (yrs) at risk assignment

20-29

117

164

0

3

284

30-39

191

208

11

16

426

40-49

190

302

12

26

530

50-59

155

192

17

25

389

60-70

77

123

15

13

228

Age (yrs) at first menarche

≥14

147

251

13

16

427

12-13

415

503

29

49

996

7-11

166

225

11

18

420

Unknown

2

10

2

0

14

Age (yrs) at FLB

<20yr

27

118

8

2

155

20-24

161

227

15

18

421

25-29

148

187

10

18

363

≥30

117

145

10

20

292

Nulliparous

277

312

12

25

626

Menopausal status

Pre

448

602

15

40

1105

Peri

67

104

4

6

181

Post

173

205

28

29

435

Unknown

42

78

8

8

136

HRT use

Never

583

814

32

59

1488

Previous user (more than 5 yr ago)

12

18

2

0

32

Previous user (less than 5 yr ago)

31

69

6

10

116

Current user

104

88

15

14

221

Number of breast biopsies

0

593

851

41

61

1546

1

98

101

7

16

222

≥2

39

37

7

6

89

Atypical hyperplasia

Absent/Unknown

727

987

55

82

1851

Present

3

2

0

1

6

First-degree female relatives with BC

0

251

336

28

26

641

1

397

544

22

40

1003

≥2

82

109

5

17

213

All female relatives with BC

0

75

139

15

10

239

1

321

479

19

29

848

≥2

334

371

21

44

770

Relatives with OC

0

555

752

27

61

1395

1

127

188

22

17

354

≥2

48

49

6

5

108

BRCA mutation status

Total mutation positive

47

45

4

14

110

BRCA1

36

22

4

8

70

BRCA2

11

23

0

6

40

Race/Ethnicity

Non-Hispanic White

651

509

36

74

1270

Hispanic

41

332

11

4

388

African American

6

42

5

0

53

Chinese

2

35

0

1

38

Filipino

0

1

0

0

1

Other Asian

4

20

2

1

27

Other

26

50

1

3

80

  1. (N = 1857).
  2. BC, breast cancer; FLB, first live birth; HRT, hormone replacement therapy; OC, ovarian cancer