Table 3 Logistic regression coefficients (ß), standard errors, and nominal significance levels of potentially predictive factors for BRCA1 or BRCA2 carriers

Baseline

-5.169

1.388

0.000

Proband breast cancer diagnosis ≤35 years

2.791

1.379

0.043

Proband breast cancer diagnosis 36-39 years

2.248

1.365

0.100

Proband breast cancer diagnosis 40-49 years

1.763

1.355

0.193

Proband breast cancer diagnosis 50-59 years

1.065

1.354

0.431

Proband bilateral breast cancer at any age

1.036

0.462

0.025

Proband ovarian cancer at any age

0.238

1.469

0.871

Proband triple-negative breast cancer at any age

1.323

0.331

0.000

For each relative with cancer:

   First degree, breast cancer diagnosis ≤39 years

0.950

0.369

0.010

   First degree, breast cancer diagnosis 40-49 years

1.450

0.386

0.000

   First degree, breast cancer diagnosis 50-59 years

1.445

0.450

0.001

   First degree, breast cancer diagnosis 60+ years

0.207

0.646

0.749

   First degree, ovarian cancer at any age

2.556

0.769

0.001

   Second degree, breast cancer diagnosis at any age

0.359

0.272

0.187

   Second degree, ovarian cancer diagnosis at any age

1.861

0.832

0.025