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Table 3 Univariate and multivariate analysis for overall survival

From: Vascular endothelial growth factor receptor-1 mRNA overexpression in peripheral blood as a useful prognostic marker in breast cancer

 

Univariate analysis

Multivariate analysis

Factors

RR

95% CI

P

RR

95% CI

P

Lymphnode metastasis (negative/positive)

2.91

1.86 to 5.03

<0.0001

2.67

1.53 to 4.96

<0.001

Hormone receptor (positive/negative)

2.37

1.61 to 3.59

<0.0001

2.65

1.62 to 4.43

0.0001

VEGFR-1 mRNA expression (negative/positive)

1.86

1.19 to 2.79

<0.01

2.00

1.19 to 3.25

<0.01

CEA (<5.0 ng/ml/ >5.1 ng/ml)

2.23

1.20 to 3.65

<0.05

1.69

0.87 to 2.95

0.11

Tumor size (small/large)

2.14

1.26 to 4.39

<0.01

1.63

0.85 to 4.13

0.16

Nuclear grade (I and II/III)

1.62

1.11 to 2.39

<0.05

1.25

0.82 to 1.89

0.29

Lymphatic involvement (negative/positive)

1.51

1.03 to 2.26

<0.05

0.99

0.62 to 1.61

0.96

Vascular involvement (negative/positive)

1.85

1.00 to 3.01

0.05

-

-

-

HER-2/NEU (negative/positive)

1.48

0.96 to 2.26

0.08

-

-

-

  1. CI, Confidence interval; RR, Relative risk