Feature | Â | Observed | Expeceted | SIR | (95% CI) | Ratio of SIRs | (95% CI) | P |
---|---|---|---|---|---|---|---|---|
Number of mitoses >50 | Absent | 81 | 31.70 | 2.56 | (2.06 to 3.18) | 2.01 | (1.23 to 3.19) | 0.002 |
 | Present | 25 | 4.86 | 5.14 | (3.47 to 7.61) |  |  |  |
Nuclear grade - malignant | Absent | 13 | 5.32 | 2.44 | (1.42 to 4.21) | 1.22 | (0.68 to 2.37) | 0.5 |
 | Present | 93 | 31.24 | 2.98 | (2.43 to 3.65) |  |  |  |
Tubule formation <10 | Absent | 21 | 9.18 | 2.29 | (1.49 to 3.51) | 1.36 | (0.83 to 2.30) | 0.2 |
 | Present | 85 | 27.38 | 3.10 | (2.51 to 3.84) |  |  |  |
Syncytial pattern ≥75% | Absent | 92 | 34.20 | 2.69 | (2.19 to 3.30) | 2.21 | (1.16 to 3.89) | 0.01 |
 | Present | 14 | 2.36 | 5.93 | (3.51 to 10.01) |  |  |  |
Circumscribed | Absent | 70 | 29.51 | 2.37 | (1.88 to 3.00) | 2.15 | (1.40 to 3.26) | <0.001 |
 | Present | 36 | 7.05 | 5.11 | (3.68 to 7.08) |  |  |  |
Pushing margins | Absent | 96 | 35.40 | 2.71 | (2.22 to 3.31) | 3.15 | (1.46 to 6.05) | 0.001 |
 | Present | 10 | 1.17 | 8.58 | (4.62 to 15.95) |  |  |  |
Lymphocytic infiltrate I - diffuse | Absent | 58 | 23.20 | 2.50 | (1.93 to 3.23) | 1.44 | (0.96 to 2.14) | 0.06 |
 | Present | 48 | 13.36 | 3.59 | (2.71 to 4.77) |  |  |  |
Lymphocytic infiltrate II-intense | Absent | 73 | 29.83 | 2.45 | (1.95 to 3.08) | 2.00 | (1.29 to 3.06) | 0.001 |
 | Present | 33 | 6.73 | 4.90 | (3.49 to 6.90) |  |  |  |
Glandular growth pattern | Absent | 47 | 10.80 | 4.35 | (3.27 to 5.79) | 0.53 | (0.35 to 0.79) | 0.001 |
 | Present | 59 | 25.76 | 2.29 | (1.77 to 2.96) |  |  |  |
Lobular growth pattern | Absent | 62 | 22.80 | 2.72 | (2.12 to 4.89) | 1.18 | (0.78 to 1.76) | 0.4 |
 | Present | 44 | 13.76 | 3.20 | (2.38 to 4.30) |  |  |  |
Trabecular growth pattern | Absent | 70 | 28.65 | 2.44 | (1.93 to 3.09) | 1.86 | (1.21 to 2.82) | 0.002 |
 | Present | 36 | 7.91 | 4.55 | (3.28 to 6.31) |  |  |  |
Tubular growth pattern | Absent | 91 | 30.34 | 3.00 | (2.44 to 3.68) | 0.80 | (0.43 to 1.39) | 0.4 |
 | Present | 15 | 6.23 | 2.41 | (1.45 to 4.00) |  |  |  |
Acinar growth pattern | Absent | 90 | 30.03 | 3.00 | (2.44 to 3.68) | 0.82 | (0.45 to 1.40) | 0.5 |
 | Present | 16 | 6.53 | 2.45 | (1.51 to 4.00) |  |  |  |
Sclerosis - extensive | Absent | 20 | 2.36 | 8.46 | (5.46 to 13.11) | 0.30 | (0.18 to 0.51) | <0.001 |
 | Present | 86 | 34.20 | 2.52 | (2.04 to 3.11) |  |  |  |
Extensive intraductal carcinoma | Absent | 81 | 30.74 | 2.34 | (2.12 to 3.28) | 1.63 | (1.00 to 2.58) | 0.03 |
 | Present | 25 | 5.82 | 4.30 | (2.90 to 6.36) |  |  |  |
Necrosis | Absent | 64 | 23.93 | 2.67 | (2.09 to 3.42) | 1.24 | (0.82 to 1.86) | 0.3 |
 | Present | 42 | 13.63 | 3.33 | (2.46 to 4.50) |  |  |  |
Apoptosis - moderate or intense | Absent | 16 | 7.30 | 2.19 | (1.34 to 3.58) | 1.40 | (0.82 to 1.86) | 0.2 |
 | Present | 90 | 29.26 | 3.08 | (2.50 to 3.78) |  |  |  |
Lymphatic invasion | Absent | 75 | 24.96 | 3.01 | (2.40 to 3.77) | 0.89 | (0.57 to 1.37) | 0.6 |
 | Present | 31 | 11.60 | 2.67 | (1.88 to 3.80) |  |  |  |
ER positive | Absent | 48 | 13.16 | 3.65 | (2.75 to 4.84) | 0.63 | (0.41 to 0.96) | 0.02 |
 | Present | 46 | 20.16 | 2.28 | (1.71 to 3.05) |  |  |  |
PR positive | Absent | 42 | 11.32 | 3.71 | (2.75 to 5.02) | 0.66 | (0.43 to 1.01) | 0.04 |
 | Present | 54 | 22.03 | 2.45 | (1.88 to 3.20) |  |  |  |