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Table 1 Number and percentage of index cases with each of the tumour morphology features

From: Tumour morphology of early-onset breast cancers predicts breast cancer risk for first-degree relatives: the Australian Breast Cancer Family Registry

Feature

All index cases

Subgroup of index cases

 

N = 452†

%

N = 375‡

%

Number of mitoses >50

71

15.7

33

8.8

Nuclear grade - malignant

386

85.4

316

84.3

Tubule formation <10

344

76.1

283

75.5

Syncytial pattern ≥75%

36

8.0

21

5.6

Circumscribed

93

20.6

56

14.9

Pushing margins

16

3.5

11

2.9

Lymphocytic infiltrate I - diffuse

162

35.8

136

36.3

Lymphocytic infiltrate II - intense

96

21.2

69

18.4

Glandular growth pattern

307

67.9

272

75.5

Lobular growth pattern

162

35.8

147

39.2

Trabecular growth pattern

109

24.1

65

17.3

Tubular growth pattern

74

16.4

64

17.1

Acinar growth pattern

87

19.3

60

16.0

Sclerosis - extensive

420

92.9

356

94.9

Extensive intraductal carcinoma

70

15.5

63

16.8

Necrosis

173

38.3

126

33.6

Apoptosis - moderate or intense

362

80.1

294

78.4

Lymphatic invasion

141

31.2

117

31.2

ER positive

226

56.4

201

61.1

PR positive

258

64.3

219

66.6

  1. † ER and PR status was available for 401 index cases.
  2. ‡ ER and PR status was available for 329 index cases.