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Table 3 Odds ratiosa for breast cancer diagnosis (15 to 39 versus 40 to 49 and 50+ years of age), by subtypeb

From: Occurrence of breast cancer subtypes in adolescent and young adult women

 

Total

HR+/HER2-

HR+/HER2+

HR-/HER2+

Triple-negative

Characteristics

15-39/40-49

15-39/50+

15-39/40-49

15-39/50+

15-39/40-49

15-39/50+

15-39/40-49

15-39/50+

15-39/40-49

15-39/50+

 

OR (95% CI)c

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

Race/ethnicity

          

   White

Reference

Reference

Reference

Reference

Reference

Reference

Reference

Reference

Reference

Reference

   Hispanic

1.58

(1.47-1.69)

3.25

(3.04-3.45)

1.59

(1.43-1.77)

3.23

(2.92-3.58)

1.51

(1.25-1.82)

2.92

(2.46-3.48)

1.36

(1.06-1.75)

2.63

(2.1-3.29)

1.52

(1.29-1.8)

3.26

(2.8-3.79)

   Asian

1.32

(1.21-1.44)

2.47

(2.28-2.67)

1.52

(1.34-1.73)

3.00

(2.67-3.38)

1.30

(1.04-1.62)

2.26

(1.84-2.77)

1.00

(0.73-1.36)

1.44

(1.09-1.9)

1.26

(0.99-1.62)

1.96

(1.57-2.45)

   Black

1.13

(1.00-1.27)

1.69

(1.52-1.89)

1.15

(0.94-1.40)

1.66

(1.38-2.00)

1.17

(0.86-1.58)

1.82

(1.37-2.42)

1.37

(0.90-2.09)

1.70

(1.18-2.46)

0.94

(0.74-1.19)

1.38

(1.11-1.71)

AJCC stage at diagnosis

          

   I/II

Reference

Reference

Reference

Reference

Reference

Reference

Reference

Reference

Reference

Reference

   III/IV

1.33

(1.24-1.43)

1.58

(1.47-1.68)

1.38

(1.24-1.55)

1.82

(1.64-2.02)

1.51

(1.26-1.80)

1.65

(1.40-1.94)

1.22

(0.97-1.54)

1.44

(1.17-1.76)

1.35

(1.13-1.60)

1.40

(1.20-1.63)

Grade

          

   Low

Reference

Reference

Reference

Reference

Reference

Reference

Reference

Reference

Reference

Reference

   High

1.82

(1.71-1.94)

2.56

(2.41-2.71)

1.75

(1.59-1.93)

2.37

(2.16-2.60)

1.29

(1.10-1.52)

1.59

(1.37-1.85)

0.85

(0.65-1.11)

1.05

(0.83-1.32)

1.53

(1.21-1.95)

2.87

(2.31-3.55)

Prior cancer

          

   1st Primary

Reference

Reference

Reference

Reference

Reference

Reference

Reference

Reference

Reference

Reference

Non-1st

primary

0.72

(0.64-0.81)

0.32

(0.29-0.36)

0.71

(0.59-0.85)

0.29

(0.24-0.35)

0.84

(0.60-1.17)

0.33

(0.24-0.44)

0.57

(0.37-0.90)

0.32

(0.21-0.48)

0.60

(0.46-0.78)

0.41

(0.32-0.51)

  1. aAdjusted for year at diagnosis, and the other variables in the table. bHuman epidermal growth factor receptor 2 (HER2), hormone receptor (HR), triple-negative (estrogen-receptor negative, progesterone-receptor negative, HER2-). cOdds ratios (95% confidence intervals).
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Breast Cancer Research

ISSN: 1465-542X

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