From: Functional characterization of the 19q12 amplicon in grade III breast cancers
Gene symbol | Gene name | Position (kb) | Copy number and expression Pearson's correlation (r) | Overexpressed when amplified (MWU) P-value |
---|---|---|---|---|
UQCRFS1 | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | 29,698 to 29,704 | 0.65* | 0.0018 |
VSTM2B | V-set and transmembrane domain containing 2B | 30,017 to 30,055 | NA | NA |
POP4 | processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) | 30,097 to 30,107 | 0.77* | 0.0018 |
PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 | 30,156 to 30,166 | 0.44* | 0.0868 |
C19ORF12 | Uncharacterised protein C19ORF12 | 30,190 to 30,206 | 0.63* | 0.0018 |
CCNE1 | Cyclin E1 | 30,303 to 30,315 | 0.66* | 0.0071 |
C19ORF2 | RPB5-mediating protein | 30,433 to 30,507 | 0.81* | 0.0001 |
ZNF536 | Zinc finger protein 536 | 30,863 to 31,049 | -0.03 | 0.6064 |
TSHZ3 | Teashirt zinc finger homeobox 3 | 31,766 to 31,840 | 0.08 | 0.5426 |