From: Relevance of PTEN loss in brain metastasis formation in breast cancer patients
 | Brain metastases (n= 21) | All primary tumors (n= 77)a | Primary tumors without relapse (n= 39) | Primary tumors with brain relapse (n= 10) | Primary tumors with other relapse (n= 17) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | n | % | n | % | Pvalueb | n | % | Pvalueb | n | % | Pvalueb | n | % | Pvalueb |
PTEN (CR1) c | 11 | 52.4 | 18 | 23.4 | 0.006 | 7 | 17.9 | 0.003 | 5 | 50.0 | n.s. | 2 | 11.8 | 0.006 |
CR2 c | 10 | 47.6 | 22 | 28.6 | n.s. | 11 | 28.2 | n.s. | 5 | 50.0 | n.s. | 3 | 17.6 | n.s. |
all AI | 13 | 61.9 | 29 | 37.7 | n.s. | 13 | 33.3 | 0.055 | 5 | 50.0 | n.s. | 5 | 29.4 | n.s. |
normal | 8 | 38.1 | 48 | 62.3 | - | 26 | 66.7 | - | 5 | 50.0 | - | 12 | 70.6 | - |