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Figure 6 | Breast Cancer Research

Figure 6

From: Silencing of HSulf-2 expression in MCF10DCIS.com cells attenuate ductal carcinoma in situ progression to invasive ductal carcinoma in vivo

Figure 6

Analysis of NTC and HSulf-2 xenografts. (A) NTC (four mice) and HSulf-2 derived (five mice/clones) xenograft lysates were subjected to Western blot analysis using antibodies against Bnip3, Bim EL, cleaved caspase 3, cleaved PARP, beta-actin, and (B) with anti-MMP-14, MMP-9 and MMP-2 antibodies. (C) NTC and HSulf-2 depleted xenografts were subjected to gelatin zymography as described in the Materials and methods to detect activities of MMP-2 and MMP-9.

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