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Figure 5 | Breast Cancer Research

Figure 5

From: Silencing of HSulf-2 expression in MCF10DCIS.com cells attenuate ductal carcinoma in situ progression to invasive ductal carcinoma in vivo

Figure 5

HSulf-2 knockdown promotes marked apoptosis in vivo. (A) TUNEL staining(green) and nuclei staining with propidium iodide (red) were performed as described in Materials and methods in NTC and HSulf-2 depleted clones at Weeks 5 and 7. (B) Quantitation of apoptotic areas (comedo lesions) in NTC and HSulf-2 depleted clones (HW11 and HW13). At least 100 fields were examined in 6 different sections of each group. *P-value < 0.05, Student t test analysis.

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