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Figure 3 | Breast Cancer Research

Figure 3

From: Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression

Figure 3

Estradiol upregulates T-cell leukemia 1A and IL-17RA in series. (A) T-cell leukemia 1A (TCL1A) and IL-17RA expression after TCL1A was knocked down in U2OS-estrogen receptor alpha (ERα) cells by four different TCL1A-specific siRNAs and by a pool of the four siRNAs. (B) TCL1A and IL-17RA expression after TCL1A was knocked down by four different TCL1A-specific siRNAs and a pool of the four siRNAs with an additional 24 hours exposure to 0.1 nM estradiol (E2). All values represent the mean ± standard error of the mean of triplicate determinations.

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