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Figure 1 | Breast Cancer Research

Figure 1

From: Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis

Figure 1

Honokiol inhibits clonogenicity and anchorage-independent growth of breast cancer cells. (a) MCF7 and MDA-MB-231 cells were treated with various concentrations of honokiol (HNK) (as indicated) and subjected to clonogenicity assay. U, untreated cells. Colonies containing > 50 normal-appearing cells were counted. *P < 0.005, compared with untreated controls. (b) Breast cancer cells were subjected to soft-agar colony-formation assay in the presence of various concentrations of honokiol for 3 weeks. Results are expressed as average number of colonies counted (in six microfields). *P < 0.001, compared with untreated controls.

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Breast Cancer Research

ISSN: 1465-542X

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