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Table 6 Subcellular distribution of 8701-BC proteins

From: Proteome analysis of breast cancer cells (8701-BC) cultured from primary ductal infiltrating carcinoma: relation to correspondent breast tissues

PROTEIN DESCRIPTION

% in Vol MB/CT

LOCALIZATION

PROTEIN DESCRIPTION

% in Vol MB/CT

LOCALIZATION

Annexin I

3.6

 

GRP 78

3.1

ER

ATP synthase β chain

5.6

MIT

HSP 60, Heat shock protein 60

1.8

MIT

β actin

0.38

CYT

MIF, Macrophage migration inhibitory factor

0.06

CYT

Calreticulin

2.96

ER

Mitochondrial 60S ribosomal protein L7/L12

0.03

MIT

Cathepsin D

0.52

LYS

PDI, Protein disulfide isomerase

3.4

ER

CK 8, Cytokeratin 8

0.9

CYT

Peptidyl prolyl cis-trans isomerase A

0.49

CYT

CK 18, Cytokeratin 18

0.28

CYT

PGDH, 15-Hydroxyprostaglandin dehydrogenase

0.11

CYT

Collagen binding protein 2

1.5

ER

Phosphatidylethanolamine-binding protein

0.16

CYT

Cytochrome C oxidase polypeptide VA

2.7

MIT

Possible cytidilate kinase

0.5

 

Elongation factor 1β

0.6

 

Proteasome, Z subunit

CYT

 

Elongation factor Tu

4.08

MIT

   

Enoyl-CoA hydratase, short chain

1.1

MIT

Superoxide dismutase

8

MIT

ERP 31, Endoplasmic reticulum protein

5.5

ER

Superoxide dismutase (Cu-Zn)

0.17

CYT

Fructose bisphosphate aldolase

0.5

CYT

TCTP, Translationally controlled tumor protein

0.59

CYT

Galectin 1

1.3

CS

Thioredoxin

0.51

 

Glutamate dehydrogenase 1

2.8

MIT

Triosephosphate isomerase

0.4

 

Glutathione S-transferase P

6.8

 

Tubulin β 2 chain

0.4

CYT

Glyceraldehyde 3-phosphate dehydrogenase

0.6

CYT

Tumor rejection antigen, GRP 94

1.5

ER

GRP 75

1.17

MIT

Ubiquitin

0.2

CYT/NU

  1. CS= cell surface; CYT= cytoplasm; MIT= mitochondria; ER= endoplasmic reticulum; NU=nucleus