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Table 1 Univariate Cox regression survival analysis of breast cancer patients with PTEN promoter variants.

From: Variants on the promoter region of PTEN affect breast cancer progression and patient survival

 

10-year breast cancer specific

5-year BDDM

Variant

P-value

HR

95% CI

P-value

HR

95% CI

-903GA

0.01521

1.90

1.13 to 3.20

0.00201

2.07

1.31 to 3.29

-975GC

0.00357

2.68

1.38 to 5.21

0.01220

2.33

1.20 to 4.52

-1026CA

0.01829

2.06

1.13 to 3.77

0.28165

1.44

0.74 to 2.79

any

0.00002

2.17

1.52 to 3.10

0.00011

1.97

1.40 to 2.79

  1. The 10-year breast cancer-specific survival and the 5-year breast cancer death or distant metastasis (BDDM) free survival analyses show significant association with reduced survival for all three PTEN promoter variants.