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Table 1 Characteristics of all assessed patients in the EORTC and MBTB cohorts

From: Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer

  

EORTC (n= 113)

MBTB (n= 255)

 

Case status

Number

%

Number

%

Age at diagnosis

<50 years

56

50%

85

33%

 

≥50 years

57

50%

168

66%

Tumor size

≤2 cm

3

3%

51

20%

 

<2 cm to ≤5

68

60%

142

56%

 

>5 cm

42

37%

39

15%

 

Unknown

0

0

23

9%

Nodal status

Negative

42

37%

88

35%

 

Positive

71

63%

142

56%

 

Unknown

0

0

25

10%

Grade

1-2

36

32%

120

47%

 

3

65

58%

119

47%

 

Unknown

12

11%

16

6%

ERa

Negative

113

100%

255

100%

 

Positive

0

0

0

0

PRb

Negative

110

97%

212

84%

 

Positive

3

3%

41

16%

 

Unknown

0

0

2

<1%

Her2c

Negative

83

73%

157

62%

 

Positive

30

27%

58

23%

 

Unknown

0

0

40

16%

  1. Assessed cases were all invasive ductal carcinomas. aER-negative status defined as <10% of tumor cells stained positive for ER by IHC (EORTC) or <10 fmol/mg protein (ligand-binding assay; MBTB); bPR-negative status defined as <10% of tumor cells stained positive for PR by IHC (EORTC) or ≤15 fmol/mg protein (ligand-binding assay; MBTB); cHer2-positive status inferred based on microarray data (EORTC) or determined by an IHC score of 3 (MBTB).