Figure 2From: Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancerLong term outcome of patients according to adjuvant chemotherapy and CD3 status. Representative immunohistochemistry (IHC) staining of CD3 (×40 objective) demonstrating (a) low and (b) dense intraepithelial infiltration of CD3+ TIL. (c) Disease-free survival (DFS) of patients treated with anthracycline-based regimens or CMF (cyclophosphamide, methotrexate, fluorouracil) relative to systemically untreated patients in CD3-high (n = 77) and -low (n = 79) subgroups. P trend , log-rank test for trend.Back to article page