Figure 7
From: Activator protein 1 (AP-1) contributes to EpCAM-dependent breast cancer invasion
Forced overexpression of c-Jun rescues breast cancer invasion in vitro following specific ablation of EpCAM. (a) Stably transduced CA1a cells (sh2), were transiently transfected with pcDNA or c-Jun constructs. After 24 hours, invasion was assessed using a matrigel transwell invasion assay. (b) Transfected cells were analyzed for c-Jun mRNA expression by RT-PCR. Actin mRNA expression served as a control for RT-PCR conditions. The results are representative of two independent experiments. EpCAM, epithelial cell adhesion molecule.