Figure 2
From: The role and function of cadherins in the mammary gland
A mammary epithelial cell showing changes in the signaling pathways that are altered when an epithelial cell goes through epithelial-mesenchymal transition. (a) Normal mammary epithelial cell showing the signaling pathways and transcription factors that affect the epithelial phenotype. (b) A mammary epithelial cell going through epithelial-mesenchymal transition (EMT) showing the signaling pathways that facilitate the mesenchymal phenotype. BMP, bone morphogenetic protein; cad, cadherin; EGFR, epidermal growth factor receptor; FGF, fibroblast growth factor; GSK, glycogen synthase kinase; miRNA, microRNA; TCF, T-cell factor; TGF transforming growth factor.